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Number of copies of each of the ~2,000 mRNAs per cell in E. coli K12 cell that grows with a doubling time of about 30 minutes

Range	1 - 10 mRNA copies/cell
Organism	Bacteria Escherichia coli
Reference	Mackie GA RNase E: at the interface of bacterial RNA processing and decay. Nat Rev Microbiol. 2013 Jan11(1):45-57. doi: 10.1038/nrmicro2930. p.51 box 2PubMed ID23241849
Comments	"In quantitative terms, where does RNase E invest its enzymatic turnovers? This can be estimated with the following assumptions. In a culture of Escherichia coli K12 that grows with a doubling time of about 30 minutes, there will be approximately 50,000 ribosomes [BNID 111527], 375,000 tRNAs [BNID 108611] (7.5 per ribosome) and perhaps a single to at most ten copies of each of the ~2,000 mRNAs per cell."
Entered by	Uri M
ID	111528