Permeability coefficient of water through egg PC-decane bilayers

Value 0.0034 cm/sec Range: Table - link cm/sec
Organism Generic
Reference Walter A, Gutknecht J. Permeability of small nonelectrolytes through lipid bilayer membranes. J Membr Biol. 1986 90(3):207-17. p.211 table 1PubMed ID3735402
Primary Source Walter, A. 1981. Nonelectrolyte Permeability of Lipid Bilayer Membranes. Ph.D. Thesis. Duke University. University Microfilms, Ann Arbor, Michigan
Method "Diffusion of small nonelectrolytes through planar lipid bilayer membranes (egg phosphatidylcholine-decane) was examined by correlating [least square regression analysis] the permeability coefficients of 22 solutes with their partition coefficients between water and four organic solvents."
Comments "If solute permeability through a lipid bilayer is governed by the same forces that determine its partitioning into nonaqueous solvents, then pm and Kp should correlate. Figure 2 shows the relationships between membrane permeability and partition coefficients into (a) hexadecane, (b) olive oil, (c) octanol, and (d) ether. The exact values of pm [membrane permeability] and Kp [partition coefficient] are given in Table 1."
Entered by Uri M
ID 110817