Fraction of ATP turnover that actin turnover is responsible for

Value 50 % Range: or ~40µmol/liter/sec %
Organism Human Homo sapiens
Reference Bernstein BW, Bamburg JR. Actin-ATP hydrolysis is a major energy drain for neurons. J Neurosci. 2003 Jan 1 23(1):1-6. p.4 right column bottom paragraphPubMed ID12514193
Primary Source Sokoloff L (1996) The metabolism of the central nervous system in vivo. In: Handbook of physiology-neurophysiology (Field J, Magoun HW, Hall VE, eds), pp 1843–1864. Washington, DC: American Physiological Society.
Comments "If one assumes total ATP use of 80µmol/liter/sec for brain tissue, which can be derived from human cerebral blood flow and metabolic rates (primary source), then actin turnover is responsible for 50% of the ATP turnover, or ~40µmol/liter/sec."
Entered by Uri M
ID 110642