Protein content in a typical haploid yeast cell

Range 4 - 5 (~50 million protein molecules/cell) pg/cell
Organism Budding yeast Saccharomyces cerevisiae
Reference Carroll KM, Simpson DM, Eyers CE, Knight CG, Brownridge P, Dunn WB, Winder CL, Lanthaler K, Pir P, Malys N, Kell DB, Oliver SG, Gaskell SJ, Beynon RJ. Absolute quantification of the glycolytic pathway in yeast: deployment of a complete QconCAT approach. Mol Cell Proteomics. 2011 Dec10(12):M111.007633. doi: 10.1074/mcp.M111.007633. p.4 right column 3rd paragraphPubMed ID21931151
Comments "Assuming 4–5 pg of protein from a typical haploid yeast cell and an average protein molecular weight of 50 kDa, this gives a total constituency of ~50 million protein molecules."
Entered by Uri M
ID 110550