| Range |
at 0.6 doublings/hour 0.47μM: at 2.5 doublings/hour 1.1μM μM
|
| Organism |
Bacteria Escherichia coli |
| Reference |
Klumpp S, Hwa T. Growth-rate-dependent partitioning of RNA polymerases in bacteria. Proc Natl Acad Sci U S A. 2008 Dec 23 105(51):20245-50. doi: 10.1073/pnas.0804953105. p.20247 right column bottom paragraphPubMed ID19073937
|
| Comments |
"As shown by the red curve in Fig. 2B, the concentration of free
RNAPs is predicted to increase from 0.47µM for a growth rate of
0.6 doublings per hour to 1.1µM for 2.5 doublings per hour. The
range of the free RNAP concentration is substantially higher than
the estimate of 30 nM made by McClure (for a doubling time of
50–60 min) based on a comparison of in vivo transcription rates
from various promoters with their Michaelis constants measured in
vitro (18)." |
| Entered by |
Uri M |
| ID |
110066 |