Tissue life span of eosinophils

Range 2 - 5 days
Organism Human Homo sapiens
Reference Park YM, Bochner BS. Eosinophil survival and apoptosis in health and disease. Allergy Asthma Immunol Res. 2010 Apr2(2):87-101. doi: 10.4168/aair.2010.2.2.87 p.88 right column bottom paragraphPubMed ID20358022
Comments "After circulating in the blood, eosinophils migrate into the tissues, probably by diapedesis at endothelial intercellular junctions by a mechanism involving cytokines and adhesion molecules. Under normal conditions, once eosinophils enter the tissues, most do not recirculate. The tissue life span of eosinophils ranges from 2 to 5 days, depending partly on the tissue studied. However, cytokines increase eosinophil survival in vitro to 14 days or longer thus, they likely also prolong eosinophil survival in vivo."
Entered by Uri M
ID 109901