Transcription initiation events at POL1 promoter during the active period in the cell cycle

Value 1.3 Min^-1 Range: ±0.72 Min^-1
Organism Budding yeast Saccharomyces cerevisiae
Reference Larson DR, Zenklusen D, Wu B, Chao JA, Singer RH. Real-time observation of transcription initiation and elongation on an endogenous yeast gene. Science. 2011 Apr 22 332(6028):475-8. p.477 left columnPubMed ID21512033
Method An idealized fluorescence time trace for transcription of a single pre-mRNA can be described by an autocorrelation function G(t), which is a discrete autocorrelation over all the transition probabilities for RNAPII
Comments Although the POL1 promoter is only active during a certain stage of the cell cycle, initiation events during this active period are stochastic and uncorrelated and occur with a frequency c=1.3±0.72min-1.
Entered by Uri M
ID 106352