Kd of FGF-2 to fibrinogen and polymerized fibrin

Range 1.3-260 nM
Organism Generic
Reference Cornwell KG, Pins GD. Enhanced Proliferation and Migration of Fibroblasts on the Surface of Fibroblast Growth Factor-2-Loaded Fibrin Microthreads. Tissue Eng Part A. 2010 Aug 28. 1st page right columnPubMed ID20673132
Primary Source Sahni A, Odrljin T, Francis CW. Binding of basic fibroblast growth factor to fibrinogen and fibrin. J Biol Chem. 1998 Mar 27 273(13):7554-9.PubMed ID9516457
Comments FGF-2 specifically binds and saturates both fibrinogen and polymerized fibrin with low Kd values ranging from 1.3nM for high affinity sites to 260nM for low affinity binding sites.
Entered by Uri M
ID 105688