HLA B-27 molecule half life

Value 4 Hours
Organism Human Homo sapiens
Reference Carreno BM, Hansen TH. Exogenous peptide ligand influences the expression and half-life of free HLA class I heavy chains ubiquitously detected at the cell surface. Eur J Immunol. 1994 Jun24 (6):1285-92.PubMed ID8206088
Method Flow cytometry, Peptide labeling and binding, Immunoprecipitation pulse/chase experiments,
Comments HLA-B27 molecules expressed on L-B27 have a t1/2 ~ 4 h, are peptide inducible and the ratio of W6/32+ to HC10+ molecules at the cell surface is approximately 3 to 1
Entered by Uri M
ID 104756