Number of amino acids added to epitope causing MHC class II conformational change
| Value | 10 aa |
|---|---|
| Organism | Mouse Mus musculus |
| Reference | Rötzschke O, Falk K, Mack J, Lau JM, Jung G, Strominger JL. Conformational variants of class II MHC/peptide complexes induced by N- and C-terminal extensions of minimal peptide epitopes. Proc Natl Acad Sci U S A. 1999 Jun 2296(13):pp. 7446 fig. 2BPubMed ID10377434 |
| Method | Binding of Peptide Ligands to Soluble HLA-DR1 Molecules and SDS/PAGE Separation. |
| Comments | Class II MHC molecules are known to exist in conformational variants. "Floppy" and "compact" forms of murine MHC molecules |
| Entered by | Uri M |
| ID | 102656 |