Number of amino acids added to epitope causing MHC class II conformational change

Value 10 aa
Organism Mouse Mus musculus
Reference Rötzschke O, Falk K, Mack J, Lau JM, Jung G, Strominger JL. Conformational variants of class II MHC/peptide complexes induced by N- and C-terminal extensions of minimal peptide epitopes. Proc Natl Acad Sci U S A. 1999 Jun 2296(13):pp. 7446 fig. 2BPubMed ID10377434
Method Binding of Peptide Ligands to Soluble HLA-DR1 Molecules and SDS/PAGE Separation.
Comments Class II MHC molecules are known to exist in conformational variants. "Floppy" and "compact" forms of murine MHC molecules
Entered by Uri M
ID 102656