Ratio between amount of vancomycin neutralized in cell wall by parental strain and resistant mutant

Value 2.13 unitless
Organism Bacteria Staphylococcus aureus
Reference Sieradzki K, Tomasz A. Inhibition of cell wall turnover and autolysis by vancomycin in a highly vancomycin-resistant mutant of Staphylococcus aureus. J Bacteriol. 1997 Apr179(8):2557-66.PubMed ID9098053
Method A highly vancomycin-resistant mutant (MIC = 100 microg/ml) of Staphylococcus aureus, mutant VM, was isolated in the laboratory by a step-pressure procedure, continued to grow and synthesize peptidoglycan in the presence of vancomycin (50 microg/ml) in the medium
Entered by Uri M
ID 102448