Occupancy of total inner membrane area by electron transport chain complexes when fermentation typically occurs

Range 8 - 9 % of total inner membrane area
Organism Bacteria Escherichia coli
Reference Szenk M, Dill KA, de Graff AMR. Why Do Fast-Growing Bacteria Enter Overflow Metabolism? Testing the Membrane Real Estate Hypothesis. Cell Syst. 2017 Aug 235(2):95-104. doi: 10.1016/j.cels.2017.06.005. p.99 left column bottom paragraphPubMed ID28755958
Comments P.99 left column bottom paragraph: "Figure 2A also shows the prediction that fermentation begins when electron transport chain complexes occupy 8%–9% of the total inner membrane area. If the membrane real estate hypothesis is valid, then why is the saturating electron transport chain occupancy not 100%? First, the integrity of the membrane requires some minimal number of lipid molecules to solvate each protein complex. Second, the cell could not function without additional, non-electron transport chain membrane proteins."
Entered by Uri M
ID 114708