Surface efficiency (number of ATP/s produced from a given amount of membrane area, electron transport chain-dependent part)

Value 3 ATP/s/nm^2 Range: ±1 ATP/s/nm^2
Organism Bacteria Escherichia coli
Reference Szenk M, Dill KA, de Graff AMR. Why Do Fast-Growing Bacteria Enter Overflow Metabolism? Testing the Membrane Real Estate Hypothesis. Cell Syst. 2017 Aug 235(2):95-104. doi: 10.1016/j.cels.2017.06.005. p.97 box 1 2nd paragraphPubMed ID28755958
Comments p.97 box 1 2nd paragraph: "The surface efficiency of the electron transport chain-dependent part can be estimated from experimental electron transport chain protein structures, abundances, and kinetics (Valgepea et al., 2013, Etzold et al., 1997). Normalizing abundances to the terminal ATP synthase, an estimated 84 nm^2 of electron transport chain is required to generate 270 ± 40 ATP/s, the maximum speed of ATP synthase (Etzold et al., 1997), resulting in a surface efficiency of only 3 ± 1 ATP/s/nm^2 (Tables S1B and S1D). The electron transport chain stoichiometry shown in the table below represents averages across growth rates (Valgepea et al., 2013) (Table S1B)."
Entered by Uri M
ID 114688