Thickness of plasma membrane and periplasm

Range plasma membrane ~6: periplasm 10-25 nm
Organism Bacteria Escherichia coli
Reference De Geyter J et al., Protein folding in the cell envelope of Escherichia coli. Nat Microbiol. 2016 Jul 26 1(8):16107. doi: 10.1038/nmicrobiol.2016.107 p.1 left column bottom paragraphPubMed ID27573113
Comments P.1 left column bottom paragraph: "The cell envelope surrounds the cytoplasm and consists of the plasma membrane (PM) and outer membrane (OM) flanking the periplasm [ref 6]. Figure 1 (left) shows the distribution of proteins in the different cell envelope compartments, associated and extracellular proteins (for the complete topological curation of E. coli proteins, see STEPdb ( Integral plasma membrane proteins (PMPs) are embedded in the PM—a ∼6-nm-thick phospholipid bilayer containing mostly phosphatidylethanolamine, phosphatidylglycerol and cardiolipin—via hydrophobic transmembrane α-helices of ∼20 amino acids. (Fig. 1, B). Some cytoplasmic proteins [refs 7,8] can also peripherally associate with the PM (Fig. 1, F1). The periplasm is 10–25-nm wide and contains peptidoglycan, a porous polymer that maintains bacterial shape and connects to the membranes via lipoproteins [refs 6,9]."
Entered by Uri M
ID 114122