Divergence time of Saccharomyces cerevisiae and S. paradoxus

Range ≈5 Mya
Organism Yeast
Reference Drummond DA, Bloom JD, Adami C, Wilke CO, Arnold FH. Why highly expressed proteins evolve slowly. Proc Natl Acad Sci U S A. 2005 Oct 4 102(40):14338-43. DOI: 10.1073/pnas.0504070102 p.14340 right column top paragraphPubMed ID16176987
Primary Source Kellis M, Patterson N, Endrizzi M, Birren B, Lander ES. Sequencing and comparison of yeast species to identify genes and regulatory elements. Nature. 2003 May 15 423(6937):241-54. DOI: 10.1038/nature01644PubMed ID12748633
Comments P.14340 left column bottom paragraph: "For S. cerevisiae, the preduplication relative K. waltii, which diverged >100 million years ago, allows evaluation of evolutionary rates relative to a single gene descended directly from the ancestral duplicated gene (ref 21) (Fig. 2). S. paradoxus, at present the closest relative of S. cerevisiae with a sequenced genome, with a divergence time of ≈5 million years ago (primary source), provides a suitable postduplication relative (Fig. 2)."
Entered by Uri M
ID 113373