Rate of transport of amino acid in the fast component

Range 240 - 420 mm/day
Organism Rat Rattus norvegicus
Reference Vahlsing HL, Hirschl RB, Feringa ER. Axoplasmic flow of tritiated proline in the corticospinal tract of the rat. Cell Tissue Res. 1981 214(2):279-87. abstract & p.285 bottom paragraphPubMed ID6162568
Method Abstract:"The rates of axoplasmic transport were studied in the corticospinal tract of the rat by injecting tritiated proline into the sensory-motor cortex and subsequently analyzing the distribution of incorporated label in the spinal cord at intervals after injection. A mathematical model of the anatomy of the corticospinal tract was developed and used in analysis of the data."
Comments P.285 bottom paragraph:"The calculated rate of transport of amino acid in the fast component (240- 420 mm/day) is consistent with the range of rates found in peripheral nerves of the rat (200-450 mm/day) (Bisby 1976 Fink et al. 1975, Komiya and Kurokawa 1978 Ochs 1972 Wood and Boegman 1975). However, this rate of flow is considerably greater than that reported by most authors for other CNS tracts in the rat."
Entered by Uri M
ID 112229