||Bacteria Escherichia coli
||Raeside C, et al., Large chromosomal rearrangements during a long-term evolution experiment with Escherichia coli. MBio. 2014 Sep 95(5):e01377-14. doi: 10.1128/mBio.01377-14. p.9 right column bottom paragraphPubMed ID25205090
||p.2 right column 2nd paragraph:"[Investigators] produced optical chromosomal maps for clones isolated from a long-term evolution experiment (LTEE) with E. coli. In this ongoing experiment, 12 populations have been independently propagated from a common ancestor in the same glucose-limited minimal medium for more than 25 years and 50,000 cell generations."
||"About 70% of the large-scale rearrangements [investigators] detected in the evolved clones occurred by homologous recombination between IS elements, and that proportion does not include new insertions of IS elements (because optical mapping cannot resolve such events)."