Potential turnover rate of traffic ATPases

Range 1 to 10 1/sec
Organism prokaryote
Reference Nikaido K, Liu PQ, Ames GF. Purification and characterization of HisP, the ATP-binding subunit of a traffic ATPase (ABC transporter), the histidine permease of Salmonella typhimurium. Solubility, dimerization, and ATPase activity. J Biol Chem. 1997 Oct 31 272(44):27745-52. p.27752 right column top paragraphPubMed ID9346917
Comments "The evidence obtained from several prokaryotic systems suggests several general properties of traffic ATPases: association between the two nucleotide-binding domains leading to cooperativity, regulation of ATPase activity by the hydrophobic components and phospholipids, affinity for ATP in the range of 100–200 µM, and potential turnover rate of 1–10 s^-1."
Entered by Uri M
ID 109035