Number of RNAPol I per rRNA gene in liver cell

Value 101 polymerases/gene
Organism Rat Rattus norvegicus
Reference French SL, Osheim YN, Cioci F, Nomura M, Beyer AL. In exponentially growing Saccharomyces cerevisiae cells, rRNA synthesis is determined by the summed RNA polymerase I loading rate rather than by the number of active genes. Mol Cell Biol. 2003 Mar23(5):1558-68. p.1567 left column 2nd paragraphPubMed ID12588976
Primary Source Harper F, Puvion-Dutilleul F. Non-nucleolar transcription complexes of rat liver as revealed by spreading isolated nuclei. J Cell Sci. 1979 Dec40: 181-92.PubMed ID536385
Comments "...average Pol I density has been measured on rRNA genes from CHO cells (41) and rat liver cells (primary source) and found to be 114 polymerases/gene and 101 polymerases/gene, respectively, which correspond to one polymerase/123 nt and one polymerase/139 nt."
Entered by Uri M
ID 108307