Size of cyclotide peptides

Range ~30 Amino acids
Organism Plants
Reference Gruber CW et al., Distribution and evolution of circular miniproteins in flowering plants. Plant Cell. 2008 Sep20(9):2471-83. p.2471 left columnPubMed ID18827180
Primary Source Craik DJ, Daly NL, Bond T, Waine C. Plant cyclotides: A unique family of cyclic and knotted proteins that defines the cyclic cystine knot structural motif. J Mol Biol. 1999 Dec 17 294(5):1327-36.PubMed ID10600388
Comments Cyclotides are ~30 amino acids in size and have the unique structural features of a head-to-tail cyclized backbone and a knotted arrangement of three-disulfide bonds, referred to as a cyclic cystine knot (CCK) motif (primary source).
Entered by Uri M
ID 107610