mRNA transcript half life in hepatocellular carcinoma cell line HepG2 and the primary fibroblast cell line Bud8

Value 10 Hours
Organism Human Homo sapiens
Reference Yang E, van Nimwegen E, Zavolan M, Rajewsky N, Schroeder M, Magnasco M, Darnell JE Jr. Decay rates of human mRNAs: correlation with functional characteristics and sequence attributes. Genome Res. 2003 Aug13(8):1863-72. doi:10.1101/gr.1272403 p.1864 left column 2nd paragraphPubMed ID12902380
Method To study the rates of mRNA degradation (“decay”) in human cells, researchers measured changes in mRNA levels following application of the RNA polymerase inhibitor Actinomycin D with Affymetrix U95Av2 high-density oligonucleotide arrays.
Entered by Uri M
ID 106867