Value |
30
min
|
Organism |
Human Homo sapiens |
Reference |
Olofsson SO, Structure and biosynthesis of apolipoprotein B. Am Heart J. 1987 Feb113(2 Pt 2):446-52.PubMed ID3812204
|
Primary Source |
K Bostrom et al, Pulse-chase studies of the synthesis and intracellular transport of apolipoprotein B-100 in Hep G2 cells,J. Biol. Chem. 1986 261: 13800-13806 |
Method |
Pulse-chase methodology in the Hep-G2 cell (a human liver carcinoma cell line) |
Comments |
The protein was transported through the cell and secreted within 30 minutes, without undergoing any major change in molecular mass, indicating that it is not synthesized as subunits that are later assembled, or cleaved into smaller components after synthesis. |
Entered by |
Uri M |
ID |
104600 |