Diffusion coefficient of protamine in p(HEMA-DMAEMA) hydrogel when loaded by imbibition

Value 55 um^2/sec
Organism Unspecified
Reference Brahim S, Narinesingh D, Guiseppi-Elie A. Release characteristics of novel pH-sensitive p(HEMA-DMAEMA) hydrogels containing 3-(trimethoxy-silyl) propyl methacrylate. Biomacromolecules. 2003 Sep-Oct4(5):1224-31PubMed ID12959587
Method An amphiphilic hydrogel of poly(2-hydroxyethyl methacrylate) cross-linked with tetraethyleneglycol diacrylate (TEGDA) was synthesized to contain the hydrophobic monomer 3-(trimethoxy-silyl) propyl methacrylate (PMA) and the pH-responsive, hydrophilic monomer N',N'-dimethylaminoethyl methacrylate (DMAEMA).
Comments For gels loaded by imbibition, the quantity of each biomolecule in the loading solution was determined before and after immersion of the gel slab. The difference between these two amounts represented the quantity of biomolecule loaded into the gel.
Entered by Uri M
ID 104040