| Comments |
P.15 right column bottom paragraph: "Current treatment of obesity targets both energy intake and expenditure, and includes dieting and physical exercise (life style changes), as well as surgery, drugs, plant extracts, and many scientifically undocumented remedies. Most of these treatments are not very effective, with a typical maximal weight loss of less than 10%, and not able to stop the epidemic. Obesity surgery is presently the most effective treatment with sustained weight loss of up to 50%. Obesity surgery consists of restricting the capacity of the stomach to accommodate ingested food and/or redirecting the flow of digesta to the lower gut, implicating gut–brain signaling as an important factor in the development and prevention of obesity [ref 3]." |