Proportion of gastric myenteric plexus neurons in which antidromic stimulation of the cervical vagus induced c-Fos expression

Range <1 % of gastric myenteric plexus neurons
Organism Rat Rattus norvegicus
Reference Berthoud HR, Neuhuber WL. Functional and chemical anatomy of the afferent vagal system. Auton Neurosci. 2000 Dec 20 85(1-3):1-17 DOI: 10.1016/S1566-0702(00)00215-0 p.13 left column 2nd paragraphPubMed ID11189015
Primary Source Zheng H, Lauve A, Patterson LM, Berthoud HR. Limited excitatory local effector function of gastric vagal afferent intraganglionic terminals in rats. Am J Physiol. 1997 Sep273(3 Pt 1):G661-9 DOI: 10.1152/ajpgi.1997.273.3.G661PubMed ID9316470
Method Primary source abstract: "To test this possibility (that Intraganglionic laminar endings (IGLEs) may serve local effector function by means of peripheral axon reflexes, analogously to dorsal root afferents), vagal afferent fibers were antidromically activated by suprathreshold electrical stimulation of the cervical vagus nerve in anesthetized rats that underwent prior supranodose vagotomy, and responses of myenteric neurons were monitored with Fos immunocytochemistry."
Comments P.13 left column 2nd paragraph: "On the other hand, antidromic stimulation of the cervical vagus induced c-Fos expression in only a very small (<1%) proportion of gastric myenteric plexus neurons, while stimulation of vagal efferents induced Fos in most enteric neurons (primary source), and it did not induce intestinal motility responses in dogs (Neya et al., 1990)."
Entered by Uri M
ID 117250