| Range |
5 - 10 fold
|
| Organism |
Rat Rattus norvegicus |
| Reference |
Lampe PD, Lau AF. The effects of connexin phosphorylation on gap junctional communication. Int J Biochem Cell Biol. 2004 Jul36(7):1171-86 DOI: 10.1016/S1357-2725(03)00264-4 p.1175 right column top paragraphPubMed ID15109565
|
| Primary Source |
Lye SJ, Nicholson BJ, Mascarenhas M, MacKenzie L, Petrocelli T. Increased expression of connexin-43 in the rat myometrium during labor is associated with an increase in the plasma estrogen:progesterone ratio. Endocrinology. 1993 Jun132(6):2380-6 DOI: 10.1210/endo.132.6.8389279PubMed ID8389279
|
| Method |
Primary source abstract: "[Investigators] measured myometrial Cx-43 messenger RNA, protein and gap junction frequency, and area in myometrial samples collected from nonpregnant rats and pregnant rats at days 5, 10, 15, 17, 18, 19, 20, 21, 22, 23 (during delivery), and 1 day postpartum and correlated these data with plasma concentrations of estradiol 17 beta and progesterone." |
| Comments |
P.1175 right column top paragraph: "A 5–10-fold increase in Cx43 mRNA and protein levels was detected immediately prior to and during labor. Cx43 protein accumulates within cytoplasmic membranes until parturition, when it is rapidly transported to the plasma membrane and assembled into gap junctions, followed by a rapid loss of the protein after delivery (e.g. primary source)." |
| Entered by |
Uri M |
| ID |
117147 |