Number of members in the connexin protein family (of which gap junctions are composed)

Range ~20 connexin family members
Organism Human Homo sapiens
Reference Lampe PD, Lau AF. The effects of connexin phosphorylation on gap junctional communication. Int J Biochem Cell Biol. 2004 Jul36(7):1171-86 DOI: 10.1016/S1357-2725(03)00264-4 p.1172 left column top paragraph & p.1174 left column bottom paragraphPubMed ID15109565
Comments P.1172 left column top paragraph: "In vertebrates, gap junctions are composed of proteins from the connexin family, which is comprised of approximately 20 members in humans." P.1174 left column bottom paragraph: "Although the completion of the human genome sequence has increased the number of known human connexins from a dozen or so to approximately 20, [investigators] have little direct experimental information on many of these newly discovered family members."
Entered by Uri M
ID 117145