Low-frequency changes in outer hair cell (OHC) length that can be captured by video microscopy

Range ≤10 Hz
Organism Guinea Pig Cavia porcellus
Reference Ashmore J. Cochlear outer hair cell motility. Physiol Rev. 2008 Jan88(1):173-210. doi: 10.1152/physrev.00044.2006 p.178 right column bottom paragraphPubMed ID18195086
Primary Source [171] Kachar B, Brownell WE, Altschuler R, Fex J. Electrokinetic shape changes of cochlear outer hair cells. Nature. 1986 Jul 24-30 322(6077):365-8 DOI: 10.1038/322365a0PubMed ID3736662
Method Primary source abstract: "Here [investigators] describe electrically evoked mechanical changes in isolated cochlear outer hair cells (OHCs) with characteristics which suggest that direct electrokinetic phenomena are implicated in the response...In the experiments described here, [they] applied sinusoidally modulated electrical potentials across isolated OHCs: this produced oscillatory elongation and shortening of the cells and oscillatory displacements of intracellular organelles."
Comments P.178 right column bottom paragraph: "Nevertheless, low-frequency changes in OHC length (i.e., up to ∼10 Hz) can be captured by video microscopy (primary source). This technique remains inherently limited by video capture rates (maximally a few tens of frames per second) unless stroboscopic techniques are employed."
Entered by Uri M
ID 117133