Characteristics of FcγR protein family (molecular mass and affinity)

Range Table - link
Organism Human Homo sapiens
Reference Saji F, Samejima Y, Kamiura S, Koyama M. Dynamics of immunoglobulins at the feto-maternal interface. Rev Reprod. 1999 May4(2):81-9 p.83 table 1PubMed ID10357095
Primary Source Anderson CL, Loone RJ. Human leukocyte IgG Fc receptors. Immunol Today. 1986 Sep7(9):264-6. doi: 10.1016/0167-5699(86)90007-1 AND Ravetch JV, Kinet JP. Fc receptors. Annu Rev Immunol. 1991 9: 457-92 DOI: 10.1146/annurev.iy.09.040191.002325 AND van de Winkel JG, Capel PJ. Human IgG Fc receptor heterogeneity: molecular aspects and clinical implications. Immunol Today. 1993 May14(5):215-21 DOI: 10.1016/0167-5699(93)90166-IPubMed ID25290629, 1910686, 8517920
Method Primary source Ravetch and Kinet abstract: "Recent advances in the structural analysis of the genes and proteins for immunoglobulin Fc domain receptors have provided a molecular characterization of this complex family." Primary source van de Winkel and Capel abstract: "In the last few years [investigators’] understanding of the Fc gamma receptor structure has increased dramatically, due to the availability of monoclonal antibodies (mAb) and cDNA probes."
Comments P.82 left column bottom paragraph: "Three distinct but closely related FcγR classes have been mapped to chromosome 1 and some of their characteristics are summarized (Table 1, Fig. 1) (primary sources)."
Entered by Uri M
ID 117058