Number of prophages in genome of E. coli O157:H7 str. Sakai (constituting 16% of total genome)

Value 18 prophages
Organism Bacteria Escherichia coli
Reference Ramisetty BCM, Sudhakari PA. Bacterial 'Grounded' Prophages: Hotspots for Genetic Renovation and Innovation. Front Genet. 2019 Feb 12 10: 65. doi: 10.3389/fgene.2019.00065 p.3 right column bottom paragraphPubMed ID30809245
Primary Source Asadulghani, M., Ogura, Y., Ooka, T., Itoh, T., Sawaguchi, A., Iguchi, A., et al. (2009). The defective prophage pool of Escherichia coli O157: prophage-prophage interactions potentiate horizontal transfer of virulence determinants. PLoS Pathog. 5:e1000408. doi: 10.1371/journal.ppat.1000408PubMed ID19412337
Comments P.3 right column bottom paragraph: "Of the completely sequenced E. coli strains, E. coli O157:H7 str. Sakai has the highest number of prophages per genome: it harbors 18 prophage elements constituting 16% of the total genome (primary source)." Primary source abstract: "A sequenced strain (O157 Sakai) possesses 18 prophages (Sp1-Sp18) that encode numerous genes related to O157 virulence, including those for two potent cytotoxins, Shiga toxins (Stx) 1 and 2."
Entered by Uri M
ID 116992