Value |
2
genome duplication events
|
Organism |
Vertebrates |
Reference |
Dehal P, Boore JL. Two rounds of whole genome duplication in the ancestral vertebrate. PLoS Biol. 2005 Oct3(10):e314 DOI: 10.1371/journal.pbio.0030314 abstractPubMed ID16128622
|
Method |
Abstract: "[Investigators] reconstructed the evolutionary relationships of all gene families from the complete gene sets of a tunicate, fish, mouse, and human, and then determined when each gene duplicated relative to the evolutionary tree of the organisms." |
Comments |
Abstract: "However, when [investigators] plotted the genomic map positions of only the subset of paralogous genes that were duplicated prior to the fish-tetrapod split, their global physical organization provides unmistakable evidence of two distinct genome duplication events early in vertebrate evolution indicated by clear patterns of four-way paralogous regions covering a large part of the human genome." |
Entered by |
Uri M |
ID |
116989 |