Fraction of myocardial cell volume occupied by mitochondrial matrix volume

Range ≤35 %
Organism Rat Rattus norvegicus
Reference Anastacio MM et al., Relationship between mitochondrial matrix volume and cellular volume in response to stress and the role of ATP-sensitive potassium channel. Circulation. 2013 Sep 10 128(11 Suppl 1):S130-5. doi: 10.1161/CIRCULATIONAHA.112.000128 p.S130 left column bottom paragraphPubMed ID24030396
Primary Source [13] Katz AM. Physiology of the Heart. 2nd ed. New York, NY: Raven Press 1992: 23–28, 98–118 [14] Bakeeva LE, Chentsov YuS, Skulachev VP. Mitochondrial framework (reticulum mitochondriale) in rat diaphragm muscle. Biochim Biophys Acta. 1978 Mar 13 501(3):349-69PubMed ID629958
Method Primary source [14] abstract: "Reconstitution of rat diaphragm mitochondria has been carried out with the use of the serial section technique."
Comments P.S130 left column bottom paragraph: "Mitochondria are dynamic structures, and the volume of myocardial cell occupied by the mitochondria is correlated with the rate of energy use [primary source 13]. Mitochondrial matrix volume composes up to 35% of cellular volume and represents a large potential space [primary sources]."
Entered by Uri M
ID 116934