| Range |
55 - 62 kDa
|
| Organism |
Unspecified |
| Reference |
Theillet FX et al., Physicochemical properties of cells and their effects on intrinsically disordered proteins (IDPs). Chem Rev. 2014 Jul 9 114(13):6661-714. doi: 10.1021/cr400695p p.6683 right column 3rd paragraphPubMed ID24901537
|
| Primary Source |
[594] Jucker M, Walker LC. Pathogenic protein seeding in Alzheimer disease and other neurodegenerative disorders. Ann Neurol. 2011 Oct70(4):532-40. doi: 10.1002/ana.22615PubMed ID22028219
|
| Comments |
P.6683 right column 3rd paragraph: "Aβ peptides occur as 40- to 42-residue proteolytic fragments of the amyloid precursor protein, which functions in synaptic stabilization and plasticity. Tau is a 55–62 kDa protein with a role in microtubule-dependent transport in the nervous system. Both proteins readily form amyloid fibrils in vitro and in vivo, and several lines of evidence support their roles in AD [Alzheimer’s disease](primary source)." |
| Entered by |
Uri M |
| ID |
116347 |