| Range |
∼20 annotated PTM sites
|
| Organism |
Human Homo sapiens |
| Reference |
Theillet FX et al., Physicochemical properties of cells and their effects on intrinsically disordered proteins (IDPs). Chem Rev. 2014 Jul 9 114(13):6661-714. doi: 10.1021/cr400695p p.6677 left column 3rd paragraphPubMed ID24901537
|
| Primary Source |
[389] Kruse JP, Gu W. Modes of p53 regulation. Cell. 2009 May 15 137(4):609-22. doi: 10.1016/j.cell.2009.04.050 [390] Meek DW, Anderson CW. Posttranslational modification of p53: cooperative integrators of function. Cold Spring Harb Perspect Biol. 2009 Dec1(6):a000950. doi: 10.1101/cshperspect.a000950PubMed ID19450511, 20457558
|
| Comments |
P.6677 left column 3rd paragraph: "Similarly, the human transcription factor and oncoprotein p53 contains ∼20 annotated PTM sites in its disordered N- and C-terminal transactivation domains (primary sources). In p53, modifications modulate protein stability, DNA binding and transcription." |
| Entered by |
Uri M |
| ID |
116291 |