| Range |
E (environmental factors) 29%: H (heredity) 5%: R (DNA replication errors) 66 %
|
| Organism |
Human Homo sapiens |
| Reference |
Tomasetti C, Li L, Vogelstein B. Stem cell divisions, somatic mutations, cancer etiology, and cancer prevention. Science. 2017 Mar 24 355(6331):1330-1334. doi: 10.1126/science.aaf9011 p.1332 middle column and right column top paragraphPubMed ID28336671
|
| Method |
Abstract: "[Investigators] studied the relationship between the number of normal stem cell divisions and the risk of 17 cancer types in 69 countries throughout the world." |
| Comments |
P.1332 middle column: "When these data are normalized for the incidence of each of these 32 cancer types in the population, [investigators] calculate that 29% of the mutations in cancers occurring in the United Kingdom were attributable to E, 5% of the mutations were attributable to H, and 66% were attributable to R. Cancer Research UK estimates that 42% of these cancer cases are preventable." |
| Entered by |
Uri M |
| ID |
115309 |