| Range |
two thirds
|
| Organism |
Human Homo sapiens |
| Reference |
Tomasetti C, Li L, Vogelstein B. Stem cell divisions, somatic mutations, cancer etiology, and cancer prevention. Science. 2017 Mar 24 355(6331):1330-1334. doi: 10.1126/science.aaf9011 abstractPubMed ID28336671
|
| Method |
Abstract: "[Investigators] studied the relationship between the number of normal stem cell divisions and the risk of 17 cancer types in 69 countries throughout the world." |
| Comments |
Abstract: "The major role of R [DNA replication errors] mutations in cancer etiology was supported by an independent approach, based solely on cancer genome sequencing and epidemiological data, which suggested that R mutations are responsible for two-thirds of the mutations in human cancers." |
| Entered by |
Uri M |
| ID |
115304 |