Volume of newly isolated hepatocyte
| Value | 6200 µm^3 |
|---|---|
| Organism | Rat Rattus norvegicus |
| Reference | Wagner BA, Venkataraman S, Buettner GR. The rate of oxygen utilization by cells. Free Radic Biol Med. 2011 Aug 1 51(3):700-12. doi: 10.1016/j.freeradbiomed.2011.05.024 p.707 right column top paragraphPubMed ID21664270 |
| Primary Source | [53] Corasanti JG, Gleeson D, Boyer JL. Effects of osmotic stresses on isolated rat hepatocytes. I. Ionic mechanisms of cell volume regulation. Am J Physiol. 1990 Feb258(2 Pt 1):G290-8 DOI: 10.1152/ajpgi.1990.258.2.G290PubMed ID2305895 |
| Comments | P.707 right column top paragraph: "However, it is clear that this is only a loose relationship, with exceptions anticipated, therefore, this relationship should be used only to make ballpark estimates. For example, newly isolated rat hepatocytes have a volume of 6.2 pl [primary source], from Fig. 3A [investigators] would predict an OCR [O2 consumption rate] of ≈ 125 amol/cell/sec. However, this rate is actually on the order of 350 amol/cell/sec (Table 2)." |
| Entered by | Uri M |
| ID | 115150 |