| Value |
60
%
|
| Organism |
Human Homo sapiens |
| Reference |
Yewdell JW, Reits E, Neefjes J. Making sense of mass destruction: quantitating MHC class I antigen presentation. Nat Rev Immunol. 2003 Dec3(12):952-61. DOI: 10.1038/nri1250 p.958 left column bottom paragraphPubMed ID14647477
|
| Primary Source |
[63] Petaja-Repo, U. E. et al. Newly synthesized human delta-opioid receptors retained in the endoplasmic reticulum are retrotranslocated to the cytosol, deglycosylated, ubiquitinated, and degraded by the proteasome. J. Biol. Chem. 276, 4416–4423 (2001) DOI: 10.1074/jbc.M007151200PubMed ID11054417
|
| Method |
Primary source: Pulse-chase experiments |
| Comments |
P.958 left column 3rd paragraph: "Fifty percent of thyrotropin receptor expressed from a transfected gene is destroyed rapidly by proteasomes [BNID 113778], which also destroy 60% of transgene-expressed epitope-tagged delta-opioid receptor [primary source]." |
| Entered by |
Uri M |
| ID |
113779 |