Fraction of peripheral myelin protein 22 synthesized by Schwann cells that is destroyed within an hour of its synthesis

Value 80 %
Organism Rat Rattus norvegicus
Reference Yewdell JW, Reits E, Neefjes J. Making sense of mass destruction: quantitating MHC class I antigen presentation. Nat Rev Immunol. 2003 Dec3(12):952-61. DOI: 10.1038/nri1250 p.958 left column bottom paragraphPubMed ID14647477
Primary Source [60] Pareek, S. et al. Neurons promote the translocation of peripheral myelin protein 22 into myelin. J. Neurosci. 17, 7754–7762 (1997)PubMed ID9315897
Comments P.958 left column 3rd paragraph: "Seventy percent of newly synthesized cystic fibrosis transmembrane conductance protein is destroyed by proteasomes [BNID 113776], whereas 80% of peripheral myelin protein 22 synthesized by Schwann cells is destroyed within an hour of its synthesis [primary source], probably by proteasomes [ref 61]."
Entered by Uri M
ID 113777