Number of nucleotides in hammerhead ribozyme

Range ~50 nts
Organism Various
Reference de la Peña M, García-Robles I, Cervera A. The Hammerhead Ribozyme: A Long History for a Short RNA. Molecules. 2017 Jan 4 22(1). pii: E78. doi: 10.3390/molecules22010078 p.1 bottom paragraphPubMed ID28054987
Primary Source [6] Prody, G.A. Bakos, J.T. Buzayan, J.M. Schneider, I.R. Bruening, G. Autolytic processing of dimeric plant virus satellite RNA. Science 1986, 231, 1577–1580 DOI: 10.1126/science.231.4745.1577 [7] Hutchins, C.J. Rathjen, P.D. Forster, A.C. Symons, R.H. Self-cleavage of plus and minus RNA transcripts of avocado sunblotch viroid. Nucleic Acids Res. 1986, 14, 3627–3640PubMed ID17833317, 3714492
Comments P.1 bottom paragraph: "The third reported catalytic RNA was a tiny ribozyme (~50 nt), the self-cleaving hammerhead ribozyme (HHR), which was found in a group of atypical plant pathogens with small circular RNA (circRNA) genomes such as viral satellite RNAs [primary source 6] and viroids [primary source 7]." Primary sources 6 & 7 investigated a plant virus & a viroid, respectively
Entered by Uri M
ID 113524