| Range |
~30 %
|
| Organism |
Eukaryotes |
| Reference |
Wang F, Durfee LA, Huibregtse JM. A cotranslational ubiquitination pathway for quality control of misfolded proteins. Mol Cell. 2013 May 9 50(3):368-78. doi: 10.1016/j.molcel.2013.03.009. p.370 right column 2nd paragraphPubMed ID23583076
|
| Primary Source |
T.J. Stevens, I.T. Arkin, Do more complex organisms have a greater proportion of membrane proteins in their genomes? Proteins, 39 (2000), pp. 417–420PubMed ID10813823
|
| Comments |
P.370 right column 2nd paragraph: "Secreted and membrane proteins comprise approximately 30% of the eukaryotic proteome (primary source) and are synthesized primarily on ER [endoplasmic reticulum]-associated polysomes. [Investigators] determined the relative contribution of cytosolic and ER-associated polysomes to total CTU [cotranslational ubiquitination] by fractionating the two types of polysomes by sequential detergent extraction (Jagannathan et al., 2011)." |
| Entered by |
Uri M |
| ID |
113358 |