Area and thickness cardiac patch should have in order to have clinical utility
Range | area 10-50cm^2: thickness several millimeters |
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Organism | Human Homo sapiens |
Reference | Vunjak-Novakovic G et al., Challenges in cardiac tissue engineering. Tissue Eng Part B Rev. 2010 Apr16(2):169-87. doi: 10.1089/ten.TEB.2009.0352. p.174 right column bottom paragraphPubMed ID19698068 |
Comments | P.174 right column bottom paragraph: "For clinical utility, an engineered cardiac patch should have an area of 10–50 cm^2 and a thickness of several millimeters. Several tissue engineering technologies are able to create a cardiac patch of a large enough surface area, but engineering viable millimeters thick cardiac constructs and their integration to the vascular supply of the host remain major challenges." |
Entered by | Uri M |
ID | 113201 |