| Comments |
P.916 middle column bottom paragraph: "[Investigators] examined methylation in two early-diverging land plants: Selaginella moellendorffii and Physcomitrella patens (fig. S1) (ref 11), both possessing Dnmt1 [CG methyltransferase], Dnmt3 [de novo methyltransferase responsible for plant CHH methylation (H = A, C, or T)], and CMT [plant-specific CHG methyltransferase] orthologs (figs. S1 to S5). S. moellendorffii TEs [transposable elements] are methylated in the CG, CHG, and CHH contexts, but unlike the angiosperms, genes have little methylation, and there is essentially no methylation around the TSS [transcriptional start site] regardless of transcription (Fig. 1, D to F, and table S1). P. patens methylation patterns closely resemble those of S. moellendorffii (table S1 and fig. S9) (ref 10). DNA methylation in these plants is strictly segregated away from genes." |