Range of Genome-wide Methylation Levels (GMLs-a measure of the percentage of all cytosines that are methylated)

Range Theobroma cacao 5%-Beta vulgaris 43%: mean ~16% %
Organism Plants
Reference Vidalis A, Živković D, Wardenaar R, Roquis D, Tellier A, Johannes F. Methylome evolution in plants. Genome Biol. 2016 Dec 20 17(1):264. doi: 10.1186/s13059-016-1127-5. p.2 left column bottom paragraphPubMed ID27998290
Primary Source [3] Niederhuth CE, Bewick AJ, Ji L, Alabady MS, Kim KD, Li Q, et al. Widespread natural variation of DNA methylation within angiosperms. Genome Biol. 2016 17: 194. DOI: 10.1186/s13059-016-1059-0 [68] Alonso C, Pérez R, Bazaga P, Herrera CM. Global DNA cytosine methylation as an evolving trait: phylogenetic signal and correlated evolution with genome size in angiosperms. Front Genet. 2015 5: 1–9. DOI: 10.3389/fgene.2015.00004PubMed ID27671052, 25688257
Comments P.2 left column bottom paragraph: "Genome size and methylome diversity- Recent comparisons of 34 angiosperm methylomes show that genome-wide methylation levels (GMLs-a measure of the percentage of all cytosines that are methylated) can vary substantially between species even within the same taxon (Fig. 1a see Additional file 2: Figure S1 for GMLs measured by HPLC and WGBS-seq). They range from as low as 5% in Theobroma cacao to as high as 43% in Beta vulgaris, with a mean of about 16% [primary sources]. While multiple factors probably contribute to these differences, interspecific variation in genome size is a strong predictor ([primary sources] see Fig. 1b)."
Entered by Uri M
ID 113095