| Range |
~5 min
|
| Organism |
Bacteria Escherichia coli |
| Reference |
Imlay JA. The molecular mechanisms and physiological consequences of oxidative stress: lessons from a model bacterium. Nat Rev Microbiol. 2013 Jul11(7):443-54. doi: 10.1038/nrmicro3032. p.446 Box 2 top paragraphPubMed ID23712352
|
| Primary Source |
[140] Gardner, P. R. & Fridovich, I. Inactivation-reactivation of aconitase in Escherichia coli. A sensitive measure of superoxide radical. J. Biol. Chem. 267, 8757–8763 (1992).PubMed ID1315737
|
| Method |
Primary source abstract: "The rapid inactivation of aconitase by O2-, previously seen to occur in vitro, was explored in vivo." |
| Comments |
P.446 Box 2 top paragraph: "Because the half-time for repair of dehydratase clusters is about 5 minutes [primary source], at any moment during aerobic growth a significant minority of the enzyme population is inactive. Any additional H2O2 stress will exacerbate the situation." |
| Entered by |
Uri M |
| ID |
112946 |