| Range |
Table - link pg/10^6cells/hour
|
| Organism |
Human Homo sapiens |
| Reference |
Leith JT, Michelson S. Secretion rates and levels of vascular endothelial growth factor in clone A or HCT-8 human colon tumour cells as a function of oxygen concentration. Cell Prolif. 1995 Aug28(8):415-30. p.422 table 2PubMed ID7548442
|
| Method |
Abstract: "To establish a quantitative relationship between VEGF [vascular endothelial growth factor] protein levels and oxygenation, [investigators] exposed exponentially growing clone A or HCT-8 human colon tumour cells in vitro (22 h at 37 degrees C) to oxygen concentrations from 21% (air mixture) to 0.01%." |
| Comments |
P.421 bottom paragraph to p.423 top paragraph: "Estimation of VEGF secretion rates in Clone A and HCT-8 cells as a function of oxygen concentration: Estimates of secretion rates are listed in Table 2, and are plotted in Figure 1(b). For clone A,
secretion rates increase by a factor of about 7-fold from 21% to 0.0 1% O2. This 7-fold increase is less than that seen for increases in intracellular levels. For HCT-8 cells, levels of VEGF in the medium were too low to measure at 21% O2." |
| Entered by |
Uri M |
| ID |
112718 |