Following Ca2+ stress, opening of mitochondrial permeability transition pore (mPTP) occurs within
| Range | 5 - 10 sec |
|---|---|
| Organism | Rat Rattus norvegicus |
| Reference | Picard M et al., Mitochondrial structure and function are disrupted by standard isolation methods. PLoS One. 2011 Mar 28 6(3):e18317. doi: 10.1371/journal.pone.0018317. p.2 right column top paragraphPubMed ID21512578 |
| Comments | P.2 right column top paragraph: "First, upon Ca2+ stress, most or all isolated mitochondria undergo mPTP opening almost simultaneously (within 5–10 seconds), whereas in permeabilized myofibers, mitochondria exhibiting a broad range of sensitivities undergo mPTP opening at different times (several minutes apart), causing a gradual and progressive inversion of the Ca2+ uptake signal." |
| Entered by | Uri M |
| ID | 112477 |