| Comments |
P.521 right column 3rd paragraph: "Elemental stoichiometry depends on virus size: The theoretical model predictions for the elemental
composition of viral heads were validated using data for seven bacteriophages that infect either heterotrophic bacteria or cyanobacteria (table 1). These bacteriophages were chosen as complete genome sequences, structural characterization (that is, the full complement of viral head proteins and their stoichiometry) and the amino acid sequences for all of the head protein components were publicly available. The elemental composition of
each bacteriophage particle was calculated from the genome sequence (carbon, nitrogen and phosphorus)
and the protein stoichiometry and amino acid content of each protein in the capsid (carbon and nitrogen only). The predictions of elemental abundance that were obtained using the biophysical scaling model strongly agreed with those that were directly measured for the seven reference phage heads (FIG. 2c table 1 Supplementary information S1 (box)), which suggests that the model can be used to predict the size-dependence of the elemental stoichiometry of intact virus particles." See note beneath table |