| Range |
Table - link
|
| Organism |
Human Homo sapiens |
| Reference |
Swidsinski A, Weber J, Loening-Baucke V, Hale LP, Lochs H. Spatial organization and composition of the mucosal flora in patients with inflammatory bowel disease. J Clin Microbiol. 2005 Jul43(7):3380-9. p.3383 table 3PubMed ID16000463
|
| Method |
P.3380 right column bottom paragraph:"Fluorescence in situ hybridization (FISH) combines the molecular identification of bacteria with the direct visualization of the relationships between the bacteria and the mucosa, providing a significant advantage over culture, PCR, and histological methods alone. In this study, the composition and spatial organization of the mucosal bacteria in patients with IBD [inflammatory bowel disease] and controls were investigated by FISH with a broad range of bacterial group-specific rRNA-targeted probes." |
| Comments |
P.3381 right column bottom paragraph:"Mucosal bacteria were found at concentrations greater than 10^9 bacteria/ml in 93% of IBD patients, 95% of patients with slc [self-limiting colitis], 65% of IBS [irritable bowel syndrome] patients, and 35% of healthy controls (Table 3). The concentrations of mucosal bacteria in CD [Crohn’s disease] patients were 2 powers higher than those in IBS patients and the controls (P < 0.001). The adherent components were most prominent in IBD (UC [Ulcerative colitis] or CD) patients. With an exception of two patients with slc, adherent bacteria wrapping the entire circumference of the intact colonic epithelium were observed exclusively in CD and UC patients (Fig. 1). Mucus-scattered and mucus ceiling bacteria predominated in the IBS and control groups." See notes beneath table |
| Entered by |
Uri M |
| ID |
112361 |