Range |
~1 hour
|
Organism |
African clawed frog Xenopus laevis |
Reference |
Audibert A, Weil D, Dautry F. In vivo kinetics of mRNA splicing and transport in mammalian cells. Mol Cell Biol. 2002 Oct22(19):6706-18. doi: 10.1128/MCB.22.19.6706-6718.2002 p.6706 right column bottom paragraphPubMed ID12215528
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Primary Source |
Jarmolowski, A., W. C. Boelens, E. Izaurralde, and I. W. Mattaj. 1994. Nuclear export of different classes of RNA is mediated by specific factors. J. Cell Biol. 124: 627-635.PubMed ID7509815
|
Comments |
P.6706 right column bottom paragraph:"Transport has been mostly studied by microinjection of in vitro-transcribed RNA into Xenopus laevis oocytes. While this approach has been useful for a biochemical characterization of the transport process, nuclear residence half-lives of the order of 1 h have been reported in most studies (primary source). Again, such a slow kinetics of export cannot represent the in vivo situation." |
Entered by |
Uri M |
ID |
112186 |